Table 1.

Susceptibility of DNAs to serum nucleases

Serum source	Decay mode*	Half-time of decay
		Control d-DNA	d-aptamer	l-aptamer
Human male	exonuclease	2h/nt	not dominant	no decay
	endonuclease	33 h	33 h	no decay
Fetal calf	exonuclease	0.2 h/nt	not dominant	50 h/nt
	endonuclease	1.9 h	2.5 h	no decay

^*Decay mode: exonuclease, apparent stepwise degradation from end; endonuclease, broad size distribution of degradation products.