Figure 3.

An example of the folding trajectory is drawn in the three-dimensional box. The x-, y-, and z-axes represent d(active sites), d(other sites), and energy. The trajectory is drawn with the real line when d(active sites) = 0 and with the broken line when d(active sites) ≠ 0. The arrows indicate the direction of the folding process. The initial structure is represented with ○. The trajectory reaches the lowest energy dominant conformation within 256 MC steps. The sequence used is the same as in Fig. 2b.