Fig. 6.
Palatal shelf adhesion after fibronectin and α5-integrin action blockage. Wild-type palatal shelves cultured for 36 hr in the presence of PBS (A, B), anti-fibronectin (C, D), or anti-α5-integrin neutralizing antibodies (E, F). (B, D and F) are sections of the cultures in (A, C, and E), respectively. In the untreated cultures, opposing mouse medial edge epithelium (MEE) adhesion (arrow in A and B) is complete. However, in the treated cultures, opposing MEE only adhered in a short length (arrow in C–F), while most of them remain separated (arrowheads in C–F). *MEE.