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. Author manuscript; available in PMC: 2009 Mar 1.
Published in final edited form as: Arch Biochem Biophys. 2007 Dec 7;471(1):20–31. doi: 10.1016/j.abb.2007.11.020

Fig. 3.

Fig. 3

Fig. 3

Fig. 3

Kinetics of CYP3A4 reduction by BMR in the presence of bromocryptine (a), testosterone (b) and 1-pyrenebutanol (c). Left panels show the changes in the concentrations of the ferrous carbonyl complexes of CYP3A4 P450 (circles) and P420 (diamonds) states and the low-spin (squares) and the high-spin (triangles) states of ferric CYP3A4. Right panels show the curves for the ferric enzyme species and the ferrous P450 carbonyl complex in semi-logarithmic coordinates.