Fig. 1.
Effect of inflammation and NOS inhibitors on expression of CYP2B6 mRNA in human hepatocytes. Cells from human hepatocyte preparation HH 1261 were treated for 24 h as shown, and then harvested for analysis of CYP2B6 mRNA expression by RT-real time PCR as described above. All treatments were carried out in triplicate. AG, aminoguanidine. Values represent means ± S.E.M. a, significantly different from control, p < 0.05.