TABLE 1.
Main clinical and virologic characteristics of the HIV-infected patientsa
| Clinical or virologic characteristic | No./ratio or value [median (range)] |
|---|---|
| Age (yr) | 50.5 (37-67) |
| Sex (M/F) | 13/2 |
| BMI | 23.7 (21.3-28.3) |
| Viral load (copies of viral genomes/ml) | 465 (50-133,560) |
| CD4 (cells/ml) | 352 (100-868) |
| Triglyceridemia (mmol/liter) | 2.3 (1.0-8.0) |
| Cholesterolemia (mmol/liter) | 5.6 (3.2-9.9) |
| ApoB/ApoA1 | 1.3 (0.6-1.5) |
| HOMA | 4.1 (1.6-14.3) |
| Lactatemia (mmol/liter) | 1.9 (0.8-2.8) |
| Duration since onset of HIV infection (yr) | 11 (5-20) |
| Treatment duration (yr) | 3.5 (1.0-4.0) |
| Duration since onset of lipodystrophy (yr) | 2.0 (0.3-3.0) |
| Patients receiving 2 or 3 NRTI ± 1 NNRTIb, no PI | 5/15 |
| Patients receiving PI and 2 NRTI | 10/15 |
| Patients receiving stavudine | 12/15 |
a
Normal values: triglyceridemia, <1.6 mmol/liter; cholesterolemia, <6.5 mmol/liter; ApoB/ApoA1 ratio, 0.44 to 0.86 for men and 0.35 to 0.69 for women; HOMA [homeostasis model assessment = fasting insulin (mU/liter) × fasting glucose (mmol/liter)/22.5], <2.5; lactatemia, <2.5 mmol/liter.
b
NNRTI, nonnucleoside reverse transcriptase inhibitors.