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. 2008 Jan 22;52(5):1743–1750. doi: 10.1128/AAC.01388-07

TABLE 5.

In vitro susceptibilities of incident baseline Scedosporium isolates to voriconazole, itraconazole, and amphotericin B and responses to voriconazole therapy

First isolate/species No. of successful therapy responses/total no. (%) MIC range of drug, μg/ml (MIC50/MIC90)
Voriconazole Itraconazole Amphotericin
S. apiospermum 15/28 (54) 0.0625-8.0 (0.25/1.0) 0.125->16.0 (0.5/2.0) 0.5->16 (4.0/>8.0)
S. prolificans 6/15 (40) 0.125-8.0 (4.0/8.0) 0.5->16.0a (16/16) 4.0-16.0a (8.0/16)
a

n = 14 isolates.