TABLE 1.
Activity of ETV against pseudotype HIV-1a
| Strain | Test site | Host cell | Inhibitor | EC50 (μΜ) ± SD |
|---|---|---|---|---|
| LAI-Luc | BMS | HeLa-CD4 | ETV | >4 |
| LAI-Luc | BMS | MT-2 | ETV | 1.2->10 |
| LAI-Luc | BMS | PBMC | ETV | >2.5 |
| NL-RLuc | BMS | MT-2 | ETV | 1.30 ± 0.02 |
| NL-Luc | Monogram | HEK-293 | ETV | 30.6b |
| NL-RLuc | BMS | MT-2 | LVD | 1.14 ± 0.95 |
| NL-RLuc | BMS | MT-2 | AZT | 0.016 ± 0.012 |
| NL-RLuc | BMS | MT-2 | EFV | 0.00034 ± 0.00000 |
a
Results are the averages of two or more independent experiments performed in duplicate ± standard deviations (SD).
b
SD not available.