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. 2008 Feb 19;52(5):1635–1641. doi: 10.1128/AAC.01071-07

TABLE 2.

Synergistic effect of PEI in combination with novobiocin and ceftazidime against different P. aeruginosa strains

Organism Antibiotic Checkerboard FIC index (interpretation) Killing curve effecta
P. aeruginosa 100609 Novobiocin 0.10 (Sb) Synergy
Ceftazidime 0.04 (S) Synergy
P. aeruginosa 25619 Novobiocin 0.35 (S) Synergy
Ceftazidime 0.09 (S) Synergy
a

Combination of 250 μg/ml PEI and one-fourth the MIC of novobiocin or ceftazidime.

b

S, synergy.