FIG. 4.

Responses of infected animals to different i.v. doses of pyocins. Female CD-1 mice were infected with LD₉₀ inocula of strain 13s P. aeruginosa. One hour after infection, cohorts of 10 animals each were treated once i.v. with each of the indicated doses of pyocin in 0.1 ml. If and when animals first appeared moribund, they were euthanized, and survivors were counted at 24 (broken line) and 48 (solid line) hours postinfection.