TABLE 1.
Bacterial counts
| Time point (h) | Mean bacterial count (SD) for:
|
|
|---|---|---|
| Blood (log no. of CFU/ml) | Spleen (log no. of CFU/g) | |
| 2a | 4.92 (0.37) | 5.31 (0.20) |
| 4a | 5.08 (0.38) | 6.23 (0.19) |
| 8a | 6.57 (0.37) | 7.15 (0.31) |
| 24a | 7.08 (0.60) | 8.29 (0.21) |
| 1a | 5.50 (0.52) | 6.73 (0.92) |
| 4a | 5.51 (0.26) | 7.65 (0.34) |
| 8a | 7.61 (0.40) | 8.17 (0.24) |
| 9a,b | 3.12 (0.45) | 4.22 (0.46) |
| 12a,b | 4.30 (NAc) | 5.45 (0.98) |
| 16a,b | 3.34 (0.06) | 5.85 (0.52) |
| 24a,b | 4.61 (0.66) | 7.68 (0.06) |
a
Bacterial counts in blood and spleen samples collected from cohorts of five animals each were determined at various times after i.p. inoculation of Pseudomonas aeruginosa strain 13s.
b
Mice were treated i.v. with 3 × 1011 pyocins at 8 h after inoculation of Pseudomonas aeruginosa 13s.
c
NA, not available.