FIG. 2.

Cl₂MDP-liposome treatment during H. pylori infection does not affect colonization levels or H. pylori-specific antibody responses. C57BL/6 mice were treated with either PBS (white symbols) or Cl₂MDP-liposomes (black symbols) from 8 days prior to the first dose of H. pylori until 10 days after the final dose of H. pylori. (A) At 10 days (n = 5) and 3 months (n = 10) after infection, mice were euthanized and stomach homogenates were plated onto selective media to determine the gastric colonization levels. (B) The H. pylori-specific serum endpoint titer was determined by ELISA 3 months after infection. The median levels of the groups in panels A and B are indicated by dashes, and each symbol represents an individual animal. Data are representative of two independently performed experiments.