TABLE 1.

Amino acid mutations identified in six CVB3 clones following selection for TBZE-029-resistant variants

CVB3 protein	Amino acid substitution	Nucleotide		Clone(s)
		Substitution	Position
2C	K107R	AAG→AGG	3620	2
2C	A224V/L	GCA→GTA/TTA	3971/3970	1, 2, 3, 4, 6/5
2C	I227V	ATT→GTT	3979	1, 2, 3, 4, 5, 6
2C	A229V	GCT→GTT	3986	1, 2, 3, 4, 5, 6
3D	S299T	TCA→ACA	6064	6