TABLE 1.
KIR and HLA genetics and characteristics of treatment-naïve recently HIV-1-infected adults
| Variable | Median (IQRa) or % | No. of patients |
|---|---|---|
| Age (yr) | 35 (32, 39) | 60 |
| HIV-1 RNA (log10 copies/ml) | 4.7 (3.8, 5.1) | 60 |
| CD4+ T-cell counts/μl | 552 (462, 748) | 60 |
| Estimated time (wk) infectedb | 13.1 (10.1, 19.1) | 60 |
| Male gender | 97 | 58 |
| Ethnicity | ||
| Asian | 8 | 5 |
| Caucasian | 68 | 41 |
| African-American | 8 | 5 |
| Latino | 15 | 9 |
| Gene carriage | ||
| KIR3DS1 | 43 | 26 |
| Homozygous | 7 | 4 |
| KIR3DL1 | 93 | 56 |
| Homozygous | 57 | 34 |
| HLA class I Bw4 | 67 | 40 |
| Bw4Ile80 | 50 | 30 |
| KIR3DS1 and Bw4Ile80 | 20 | 12 |
| HLA-B*57 | 12 | 7 |
| HLA-B*58 | 7 | 4 |
| B*58 supertype | 18.3 | 11 |
| KIR3DS1 and B*58 supertype | 5 | 3 |
a
IQR, interquartile range (25th, 75th percentiles).
b
Estimated time since HIV-1 infection (see Materials and Methods for reference).