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Amino acid sequence alignment of E7 pocket protein binding regions of HPV-1, HPV-11, and HPV-18. Numbers represent the position of the first residue displayed. The solid underlined sequence indicates the conserved LxCxE pocket protein binding domain. The dashed underlined sequence signifies the consensus SxxD/E CKII motif. Like symbols above or below the residues denote mutated residues in mutant forms of E7 characterized in this study.
