Table 4.
Covariate | Attainment of SBP goal | Attainment of DBP goal | ||||
---|---|---|---|---|---|---|
Hazard ratio | 95% CI | p-value | Hazard ratio | 95% CI | p-value | |
Age (years) | 0.99 | 0.98–1.00 | 0.17 | 1.00 | 0.99–1.01 | 0.64 |
Male gender | 0.71 | 0.54–0.95 | 0.020 | 0.77 | 0.58–1.03 | 0.07 |
African American race | 1.02 | 0.67–1.55 | 0.91 | 1.06 | 0.69–1.63 | 0.80 |
Diabetes | 0.83 | 0.62–1.12 | 0.23 | 1.31 | 0.96–1.78 | 0.09 |
BMI > 30 kg/m2 | 0.76 | 0.58–1.00 | 0.048 | 0.67 | 0.50–0.90 | 0.008 |
Therapeutic intensity score# | 1.00 | 0.90–1.12 | 0.98 | 1.02 | 0.91–1.14 | 0.75 |
Difference from SBP or DBP goal at baseline | 0.99 | 0.98–0.99 | <0.001 | 0.97 | 0.96–0.98 | <0.001 |
eGFR <60 ml/min/1.73 m2 | 0.74 | 0.54–1.02 | 0.07 | 0.85 | 0.61–1.18 | 0.32 |
Albuminuria status*: | ||||||
Macro-albuminuria | 0.54 | 0.35–0.83 | 0.005 | 0.87 | 0.56–1.36 | 0.54 |
Micro-albuminuria | 0.71 | 0.53–0.97 | 0.032 | 0.82 | 0.60–1.13 | 0.23 |
Note: Model adjusted for visit month (time).
With normal albumin as reference. Normal = <30 mg/g creatinine; micro-albuminuria = 30–300 mg/g creatinine; macro-albuminuria = >300 mg/g creatinine.
Anti-hypertension therapeutic intensity score: calculated as daily dose/maximum FDA approved dose, summed across medication class.
Abbreviations: SBP, systolic blood pressure; DBP, diastolic blood pressure.