Table 3.
Sensitivity, Specificity, Positive and Negative Predictive Value for Retinopathy At Different Fasting Plasma Glucose Cut Offs. To convert from mmol/l to mg/dl, multiply by 18.
| Fasting plasma glucose threshold | No of retinopathy cases/Total no of participants (%)
|
Sensitivity (%) | Specificity (%) | Positive Predictive Value (%) | Negative Predictive Value (%) | Positive Likelihood Ratio | Negative Likelihood Ratio | |
|---|---|---|---|---|---|---|---|---|
| Below the cut off | Above the cut off | |||||||
| The Blue Mountains Eye Study | ||||||||
| ≥ 7.8 mmol/l | 314/3030 (10.4) | 50/132 (37.9) | 37.9 | 89.6 | 37.9 | 89.6 | 3.6 | 0.7 |
| ≥ 7.0 mmol/l | 310/2990 (10.4) | 54/172 (31.4) | 31.4 | 89.6 | 31.4 | 89.6 | 3.0 | 0.8 |
| ≥ 5.6 mmol/l | 262/2568 (10.2) | 102/594 (17.2) | 17.2 | 89.8 | 17.2 | 89.8 | 1.7 | 0.9 |
| The Australian Diabetes, Obesity and Lifestyle Study | ||||||||
| ≥ 7.8 mmol/l | 144/1884 (7.6) | 66/298 (22.2) | 22.2 | 92.4 | 22.2 | 92.4 | 2.9 | 0.8 |
| ≥ 7.0 mmol/l | 128/1722 (7.4) | 82/460 (17.8) | 17.8 | 92.6 | 17.8 | 92.6 | 2.4 | 0.9 |
| ≥ 5.6 mmol/l | 57/773 (7.4) | 153/7.89 (10.9) | 10.9 | 92.6 | 10.9 | 92.6 | 1.5 | 1.0 |
| The Multi-Ethnic Study of Atherosclerosis | ||||||||
| ≥ 7.8 mmol/l | 772/5611 (13.8) | 187/468 (40.0) | 40.0 | 86.2 | 40.0 | 86.2 | 2.9 | 0.7 |
| ≥ 7.0 mmol/l | 725/5404 (13.4) | 234/675 (34.7) | 34.7 | 86.6 | 34.7 | 86.6 | 2.6 | 0.8 |
| ≥ 5.6 mmol/l | 450/3524 (12.8) | 509/2555 (19.9) | 19.9 | 87.2 | 19.9 | 87.2 | 1.6 | 0.9 |