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. Author manuscript; available in PMC: 2008 Apr 28.
Published in final edited form as: Biol Psychiatry. 2007 Nov 5;63(7):642–649. doi: 10.1016/j.biopsych.2007.09.019

Figure 5.

Figure 5

The Localized Deletion of BDNF in the CA1 or DG Region does not Alter Preference for a Natural Reward in the Sucrose Preference Paradigm. (A) Male floxed BDNF mice injected with either AAV-Cre or AAV-GFP in the CA1 display a similar preference for the sucrose solution (AAV-GFP, n = 12; AAV-Cre, n = 11). (B) Male floxed BDNF mice with a localized deletion of BDNF in the DG region have indistinguishable levels of intake of the sucrose solution compared to injected AAV-GFP mice. The total intake of liquid (water plus sucrose solution) was unchanged between the groups (p > 0.05). Results are presented as mean of sucrose preference (the percentage of sucrose solution ingested relative to the total amount of liquid consumed) ± SEM (AAV-GFP, n = 12; AAV-Cre, n = 13).