Figure 5.
Simultaneous monitoring of two populations of circulating cancer cells. Detected events are shown after the injection of 5 × 105 Qdot585 stained (low metastatic potential) MCF-7 cells simultaneously with 1 × 106 Qdot665 stained (high metastatic potential) 435 cells into the same mouse at time 0. The frequency was calculated as the number of events counted in the short wavelength S-channel (open markers) or long wavelength L-channel (closed markers) within 430 seconds. The experiment was repeated in three different mice, and the average results are shown, with error bars indicating the variation over the three animals. Both axes are log scale.