Non-linear regression of the BaSO4 relative peak intensity with the number of loading cycles using a power-law, y = A·xb. The region of analysis included either the micro-CT image of the entire specimen cross-section or a subregion that excluded the free surfaces of beams and endosteal vasculature, as shown in Figure 2. Specimens regarded as outliers included two specimens that were observed to be over-stained and four specimens that exhibited macroscopic cracks propagating from the imaged notch (Fig. 8).