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. 1977 May;130(2):676–683. doi: 10.1128/jb.130.2.676-683.1977

Functional capacities and the adenylate energy charge in Escherichia coli under conditions of nutritional stress.

M Walker-Simmons, D E Atkinson
PMCID: PMC235267  PMID: 122511

Abstract

Functional capacities in Escherichia coli cells starved for glucose were examined by comparing protein synthesis, utilization of new substrates, and maintenance of viability with the adenylate energy charge of the culture. When growth ceased because of glucose exhaustion in an E. coli culture, the energy charge dropped from 0.90 to about 0.80. During this time, the viable-cell count and the capacity for protein synthesis and for induction of new enzymes were maintained only if other substrates were available in the medium. The culture could be maintained for many hours without growth or death if glucose was added slowly; the energy charge in this case stabilized at about 0.80. A consistent transient decrease in the energy charge to around 0.80, accompanied by a decrease in protein synthesis, was also observed during the adaptation from glucose to other substrates during diauxic growth on glucose and glycerol or lactose.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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