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CyPA incorporation into SIVmac particles that harbor different portions of the HIV-1 CyPA-binding site. HeLa cells transfected with Gag polyprotein expression constructs were metabolically labeled with [35S]methionine, and the protein content of sucrose-purified viral particles was compared by SDS/PAGE. The parental and chimeric gag genes expressed are indicated above each lane. A and B show the results of separate experiments.
