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. 1997 Oct 14;94(21):11573–11576. doi: 10.1073/pnas.94.21.11573

Figure 1.

Figure 1

Mouse lung seeding in vivo by GFP human lung tumor cells. (A) GFP-transfected cells selected in 50 nm MTX. Approximately 1.0 × 107 cells were injected into the tail vein of nude mice. (B) The excised mouse lung 7 days after cell injection. Numerous fluorescent small colonies can be visualized on the nude mouse lung, with a size of up to approximately 150 microns. Portions of this lung were then explanted into collagen-sponge-gel-matrix-supported histoculture (Bar = 500 μm.)

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