Figure 4.
Calmodulin inhibits InsP3-evoked Ca2+ release from cerebellar microsomes. Cerebellar microsomes were loaded with 45Ca2+ in the absence (○) or presence (•) of 10 μM calmodulin before addition of the indicated concentrations of InsP3 in the continued presence or absence of calmodulin. The results (means ± SEM of 3–17 independent experiments, each performed in triplicate) show the amount of Ca2+ released during the 45-s incubation with InsP3.