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. 2008 Mar 29;23(4):411–417. doi: 10.1007/s11606-007-0477-9

Table 2.

Cohort Characteristics for Four Groups, by Decision Support Tool Recommendation for Anticoagulation and Actual Treatment with Warfarin

  Anticoagulation per DST No anticoagulation per DST
Warfarin treatment No Warfarin treatment   Warfarin treatment No Warfarin treatment  
n % n % p n % n % p
Observations 298 9.9 2,710 90.1 203 6.5 2,912 93.5
Age, mean (SD) 68.6 (13.7) 74.6 (14.3) <0.01 76.1 (10.1) 78.6 (12.1) <0.01
White 241 80.9 2,100 77.5 0.18 175 86.2 2,354 80.8 0.06
Female 209 70.1 2,069 76.3 0.02 155 76.4 2,154 74 0.45
Hypertension 217 72.8 1,791 66.1 0.02 59 29.1 773 26.5 0.43
DM 132 44.3 1,161 42.8 0.63 22 10.8 335 11.5 0.77
CHF 167 56 1,505 55.5 0.87 39 19.2 630 21.6 0.42
Prior MI 55 18.5 478 17.6 0.73 22 10.8 336 11.5 0.76
Prior stroke 21 7 236 8.7 0.33 20 9.9 250 8.6 0.54
Recent stroke 5 1.7 42 1.5 0.87 15 7.4 168 5.8 0.34
Prior GI bleed 3 1 19 0.7 0.47* 16 7.9 402 13.8 0.02
Prior ICH 0 0 33 1.2 0.07* 0 0 26 0.9 0.41*
Prior other bleed 13 4.4 147 5.4 0.44 6 3 94 3.2 0.83
Comorbidity (any of the 3) 25 8.4 301 11.1 0.15 60 29.6 1,193 41 <0.01
 Anemia 14 4.7 178 6.6 0.21 47 23.2 837 28.7 0.09
 Renal disease 9 3 162 6 0.04 12 5.9 413 14.2 <0.01
 Recent MI 6 2 68 2.5 0.6 9 4.4 182 6.3 0.3
Substance abuse 17 5.7 94 3.5 0.05 6 3 95 3.3 0.81
Psychiatric Dx 45 15.1 559 20.6 0.02 23 11.3 530 18.2 0.01
Social factors 50 16.8 655 24.2 <0.01 47 23.2 598 20.5 0.37
Non-compliance 97 32.6 1,151 42.5 <0.01 72 35.5 1,079 37.1 0.65
GI Med 152 51 1,528 56.4 0.08 93 45.8 1,537 52.8 0.05
Analgesics 228 76.5 1,984 73.2 0.22 157 77.3 1,897 65.1 <0.01
Steroids + 84 28.2 756 27.9 0.92 47 23.2 689 23.7 0.87
Other GI/anemia risk Rx 28 9.4 277 10.2 0.65 18 8.9 365 12.5 0.12
All cause mortality 91 30.5 1,323 48.8 <0.01 74 36.5 1,691 58.1 <0.01

p: Chi square

*Fisher’s exact