Table 2.
Anticoagulation per DST | No anticoagulation per DST | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Warfarin treatment | No Warfarin treatment | Warfarin treatment | No Warfarin treatment | |||||||
n | % | n | % | p | n | % | n | % | p | |
Observations | 298 | 9.9 | 2,710 | 90.1 | 203 | 6.5 | 2,912 | 93.5 | ||
Age, mean (SD) | 68.6 | (13.7) | 74.6 | (14.3) | <0.01 | 76.1 | (10.1) | 78.6 | (12.1) | <0.01 |
White | 241 | 80.9 | 2,100 | 77.5 | 0.18 | 175 | 86.2 | 2,354 | 80.8 | 0.06 |
Female | 209 | 70.1 | 2,069 | 76.3 | 0.02 | 155 | 76.4 | 2,154 | 74 | 0.45 |
Hypertension | 217 | 72.8 | 1,791 | 66.1 | 0.02 | 59 | 29.1 | 773 | 26.5 | 0.43 |
DM | 132 | 44.3 | 1,161 | 42.8 | 0.63 | 22 | 10.8 | 335 | 11.5 | 0.77 |
CHF | 167 | 56 | 1,505 | 55.5 | 0.87 | 39 | 19.2 | 630 | 21.6 | 0.42 |
Prior MI | 55 | 18.5 | 478 | 17.6 | 0.73 | 22 | 10.8 | 336 | 11.5 | 0.76 |
Prior stroke | 21 | 7 | 236 | 8.7 | 0.33 | 20 | 9.9 | 250 | 8.6 | 0.54 |
Recent stroke | 5 | 1.7 | 42 | 1.5 | 0.87 | 15 | 7.4 | 168 | 5.8 | 0.34 |
Prior GI bleed | 3 | 1 | 19 | 0.7 | 0.47* | 16 | 7.9 | 402 | 13.8 | 0.02 |
Prior ICH | 0 | 0 | 33 | 1.2 | 0.07* | 0 | 0 | 26 | 0.9 | 0.41* |
Prior other bleed | 13 | 4.4 | 147 | 5.4 | 0.44 | 6 | 3 | 94 | 3.2 | 0.83 |
Comorbidity (any of the 3) | 25 | 8.4 | 301 | 11.1 | 0.15 | 60 | 29.6 | 1,193 | 41 | <0.01 |
Anemia | 14 | 4.7 | 178 | 6.6 | 0.21 | 47 | 23.2 | 837 | 28.7 | 0.09 |
Renal disease | 9 | 3 | 162 | 6 | 0.04 | 12 | 5.9 | 413 | 14.2 | <0.01 |
Recent MI | 6 | 2 | 68 | 2.5 | 0.6 | 9 | 4.4 | 182 | 6.3 | 0.3 |
Substance abuse | 17 | 5.7 | 94 | 3.5 | 0.05 | 6 | 3 | 95 | 3.3 | 0.81 |
Psychiatric Dx | 45 | 15.1 | 559 | 20.6 | 0.02 | 23 | 11.3 | 530 | 18.2 | 0.01 |
Social factors | 50 | 16.8 | 655 | 24.2 | <0.01 | 47 | 23.2 | 598 | 20.5 | 0.37 |
Non-compliance | 97 | 32.6 | 1,151 | 42.5 | <0.01 | 72 | 35.5 | 1,079 | 37.1 | 0.65 |
GI Med | 152 | 51 | 1,528 | 56.4 | 0.08 | 93 | 45.8 | 1,537 | 52.8 | 0.05 |
Analgesics | 228 | 76.5 | 1,984 | 73.2 | 0.22 | 157 | 77.3 | 1,897 | 65.1 | <0.01 |
Steroids + | 84 | 28.2 | 756 | 27.9 | 0.92 | 47 | 23.2 | 689 | 23.7 | 0.87 |
Other GI/anemia risk Rx | 28 | 9.4 | 277 | 10.2 | 0.65 | 18 | 8.9 | 365 | 12.5 | 0.12 |
All cause mortality | 91 | 30.5 | 1,323 | 48.8 | <0.01 | 74 | 36.5 | 1,691 | 58.1 | <0.01 |
p: Chi square
*Fisher’s exact