Table 2. Univariate and multivariate analyses of immune cells and clinicopathological features using the Cox proportional hazard regression model.

	Univariate		Multivariate
Variable	Hazard ratio (95% CI)	P-value	Hazard ratio (95% CI)	P-value
Gender (male/female)	2.812 (0.872–9.070)	0.0835
Age (⩾62 vs <62) (years)	1.404 (0.783–2.519)	0.2543
pT classification (3/4 vs 1/2)	4.164 (2.238–7.747)	<0.0001	2.564 (1.305–5.038)	0.0063
pN classification (1 vs 0)	5.880 (2.885–11.985)	<0.0001	5.051 (2.273–11.236)	<0.0001
pM classification (1 vs 0)	3.056 (1.615–5.780)	0.0006	1.067 (0.532–2.141)	0.8556
pStage (III/IV vs I/II)	7.828 (3.969–15.437)	<0.0001
CD4 status (abundant vs scanty)	0.350 (0.184–0.664)	0.0013	0.778 (0.374–1.619)	0.5022
CD8 status (abundant vs scanty)	0.451 (0.248–0.819)	0.0089	0.502 (0.259–0.974)	0.0417
Foxp3 status (low vs high)	2.474 (1.338–4.577)	0.0039	2.239 (1.172–4.275)	0.0146
CD4/8 (CD4/8(+/+) vs others)	0.208 (0.088–0.492)	0.0003	0.250 (0.130–0.603)	0.0020
Foxp3 status (low vs high)	2.474 (1.338–4.577)	0.0039	1.784 (0.949–3.353)	0.0722

CI, confidence interval.