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. 2008 Mar 18;98(7):1217–1225. doi: 10.1038/sj.bjc.6604289

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Copyright © 2008 Cancer Research UK

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Schematic diagram showing the binding site of PR1A3 on CEA. The antibody binds at a site involving parts of the GPI anchor and the B3 domain of CEA. Access to the epitope appears to be blocked when CEA is released from the cell.