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. 2008 Mar 18;98(7):1217–1225. doi: 10.1038/sj.bjc.6604289

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Copyright © 2008 Cancer Research UK

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Comparison of humanised IgG1 and murine IgG1 isotypes of PR1A3 in fluorescence-based ADCC assays using human PBMCs as effectors and the MKN45 cell line. Effector:target ratios of 100 : 1 were used in all assays. Columns represent mean % lysis from triplicate wells containing both target and effector cells with no, or with increasing concentrations of hPR1A3.