Table 1. Baseline characteristics.
Baseline characteristic | Number of patients (N=57) | % |
---|---|---|
Age, years | ||
Median | 66 | |
Range | 33–88 | |
Sex | ||
Male | 32 | 56 |
Female | 25 | 44 |
Tumour stage | ||
T1–2 | 12 | 21 |
T3–4 | 43 | 75 |
N0 | 19 | 33 |
N1–2 | 33 | 58 |
Preoperative treatment | ||
RT | 38 | 67 |
RCT | 19 | 33 |
Surgery | ||
Abdominoperineal resection | 15 | 26 |
Sphincter-preserving surgery | 38 | 67 |
TS | ||
Low | 22 | 39 |
High | 32 | 56 |
P53 | ||
Negative | 13 | 23 |
Positive | 44 | 77 |
VEGF | ||
Negative | 21 | 37 |
Positive | 31 | 54 |
P21 | ||
Negative | 24 | 42 |
Positive | 32 | 56 |
MLH1 | ||
Preserved | 43 | 75 |
Altered | 14 | 25 |
MSH2 | ||
Preserved | 44 | 77 |
Altered | 13 | 23 |
Abbreviations: RT=radiotherapy; RCT=radiochemotherapy; TS=thymidilate synthase; VEGF=vascular endothelial growth factor.