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|
NF-kB activation
| |||
|---|---|---|---|
| Yes (4) | No (16) | ||
| PR | 0 | 10 | P<0.05 |
| SD | — | 5 | P<0.05 |
| PD | 4 | 1 | P<0.05 |
| EGFR overexpression | |||
| Yes (11) | No (9) | ||
| PR | 6 | 4 | P=NS |
| SD | 1 | 4 | P=NS |
| PD | 4 | 1 | P=NS |
| EGFR amplification | |||
| Yes (3) | No (17) | ||
| PR | 1 | 9 | |
| SD | 2 | 3 | |
| PD | — | 5 | |
EGFR=epidermal growth factor receptor; NF-kB=nuclear factor-kB; NS=non-significant; PR=partial response; PD=progressive disease; SD=stable disease.
