Table 3. Results of multivariate analysis of 3-year OS from first surgery, menstrual cycle according to LMP incorporated in its continuous form.
| Estimate | Standard error | Hazard ratio [95% confidence interval] | df | Likelihood ratio statistic | P-value | |
|---|---|---|---|---|---|---|
| Nottingham Prognostic Index | 0.85 | 0.16 | 2.34 [1.73, 3.18] | 1 | 29.77 | <0.0001 |
| Hormone therapy (yes vs no) | 0.65 | 0.41 | 1.91 [0.85, 4.30] | 1 | 2.66 | 0.10 |
| Radiotherapy (yes vs no) | −0.22 | 0.47 | 0.80 [0.32, 2.02] | 1 | 0.21 | 0.65 |
| Chemotherapy (yes vs no) | −0.64 | 0.51 | 0.53 [0.19, 1.43] | 1 | 1.45 | 0.23 |
| Type of first surgery | 2 | 3.12 | 0.21 | |||
| Mastectomy vs excision biopsy | 1.08 | 0.75 | 2.93 [0.67, 12.87] | |||
| Lumpectomy vs excision biopsy | 0.63 | 0.78 | 1.87 [0.40, 8.68] | |||
| Day of menstrual cycle | 0.02 | 0.01 | 1.02 [0.995, 1.042] | 1 | 2.13 | 0.14 |
LMP=last menstrual period; OS=overall survival.