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. 2007 Dec 18;98(1):154–160. doi: 10.1038/sj.bjc.6604142

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Copyright © 2008 Cancer Research UK

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Representative images of FISH-positive results on cytological specimens (EGFR gene: red signals; chromosome 7: green signals). (A) Amplification of the EGFR gene with tight EGFR gene clusters; (B) high polysomy of the EGFR gene in the cancer cells. FISH=fluorescence in situ hybridisation; EGFR=epidermal growth factor receptor (see online version for colour figure).