Table 5.

Vision function in HIV individuals without retinitis: significant^* associations between demographic, health, virologic, and immunologic measures with impaired visual acuity^† (worse than 20/40 Snellen)

	No. eyes	Odds ratio of Impaired VA (95% CI)	P
Number of opportunistic infections			<0.001
0	582	2.9 (1.7 – 4.9)
1+	2084	1.0 (reference)
Karnofsky score			0.001
< 80	431	5.0 (1.9 – 13.3)
80	805	2.2 (0.9 – 5.6)
90	1033	2.0 (0.8 – 4.8)
100	397	1.0 (reference)

^*Based on backward stepwise logistic regression of 18 covariates (cohort, sex, race, age, education, insurance status, hemoglobin level, Karnofsky score, HIV risk factor, time since AIDS diagnosis, no. of OIs, HAART status, HIV viral load, CD4 count, nadir CD4 count, CD8 count, CMV viral load, and right vs. left eye) with probability of removal p>0.05.

^†Event rate is 2.9% (76/2666).