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. 2008 Apr 21;5:50. doi: 10.1186/1743-422X-5-50

Figure 2.

Figure 2

Activation of the human and murine lymphotactin receptor by human, murine and viral agonists. Dose-response experiments measuring IP3 turnover in COS-7 cells transiently transfected with the human and murine lymphotactin receptors XCR1 and mXCR1 and the promiscuous chimeric G-protein Gqi4myr using increasing concentrations of the agonists XCL1 (black square), mXCL1 (black triangle) and vCCL3 (white circle). The thin line indicate the EC50 for the particular ligand (assuming Emax equal to that of vCCL3). All assays were performed in duplicate.