Skip to main content
. 2008 Apr 21;5:50. doi: 10.1186/1743-422X-5-50

Table 1.

Chemokines encoded by human viruses and their human and murine chemokine receptor targets.

Virus Gene Protein human chemokine receptor targets Ref also targeting the corresponding murine chemokine receptor Ref
CMV UL146 vCXCL1 Selective CXCR2 agonist 11 No 20
UL147 vCXCL2 ?
HHV6a U83B vCCL4 Selective CCR2 agonist 9 ?
HHV8 K6 vCCL1 (vMIP-I) Selective CCR8 agonist 3,5,10 Yes 18
K4 vCCL2 (vMIP-II) Broadspectrum chemokine receptor
antagonist
CCR1 6,7 Yes 19
CCR2 6,7 Yes 19
CCR5 6,7 Yes 19
XCR1 7 No This paper
CX3CR1 7 ?
CXCR4 6,7 ?
CCR3 agonist 17 ?
K4.1 vCCL3 (vMIP-III) Selective XCR1 agonist 10 No This paper
MCV MC148 MCC Selective CCR8 antagonist 7 No 18

aThe protein product from the U83 gene of HHV6A has not been included as its signal sequence include a premature stop codon.