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. 2008 Apr 28;105(17):6409–6414. doi: 10.1073/pnas.0710766105

Table 2.

Measurements of ATP energy metabolism and brain activity under four varied anesthesia conditions

Anesthesia Condition PCr, mM ATP, mM Pi, mM kf,CK, s−1 kf,ATPase, s−1 Ff,CK, μmol/g/min Ff,ATPase, μmol/g/min EEG SEI
IsoF 5.0 3.0 1.3 0.24 ± 0.02 0.17 ± 0.03 65.4 ± 7.3 12.1 ± 1.9 0.74 ± 0.06
α-Ch 4.99 ± 0.21 3.03 ± 0.21 1.28 ± 0.13 0.21 ± 0.03* 0.13 ± 0.02* 59.5 ± 9.3 9.7 ± 1.2* 0.67 ± 0.04*
Low-Pen 4.95 ± 0.14 3.05 ± 0.15 1.26 ± 0.17 0.21 ± 0.02* 0.12 ± 0.02* 58.4 ± 10.5 8.6 ± 1.0* 0.61 ± 0.03*
High-Pen 4.60 ± 0.29* 2.98 ± 0.10 1.85 ± 0.19* 0.19 ± 0.03* 0.07 ± 0.03* 46.8 ± 10.0* 6.4 ± 1.9* 0.44 ± 0.08*

*The measured parameter was statistically significant different (P < 0.05 with unpaired two-tailed t test) from that measured under the IsoF condition.