Table 3. Toxicity.
Number of patients
|
||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Level 1 (n=3) | Level 2 (n=5) | Level 3 (n=6) | Level 4 (n=7) | |||||||||
Grade | 1,2 | 3 | 4 | 1,2 | 3 | 4 | 1,2 | 3 | 4 | 1,2 | 3 | 4 |
Leucocytes | 3 | 0 | 0 | 3 | 0 | 0 | 3 | 0 | 0 | 6 | 0 | 0 |
Neutrophiles | 1 | 1 | 0 | 1 | 0 | 0 | 2 | 0 | 0 | 3 | 0 | 0 |
Haemoglobin | 0 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 0 | 4 | 0 | 0 |
Platelets | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 0 |
Anorexia | 2 | 0 | 0 | 3 | 0 | 0 | 1 | 3 | 0 | 5 | 0 | 0 |
Nausea | 0 | 0 | 0 | 2 | 0 | 0 | 1 | 3 | 0 | 6 | 0 | 0 |
Vomiting | 1 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 3 | 0 | 0 |
Diarrhoea | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Mucositis | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Fatigue | 2 | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 0 | 2 | 0 | 0 |
Gastritis | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Duodenal ulcer | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 |
Bilirubin | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Hypoalbuminaemia | 1 | 0 | 0 | 1 | 0 | 0 | 3 | 0 | 0 | 5 | 0 | 0 |
AST | 1 | 0 | 0 | 1 | 0 | 0 | 4 | 0 | 0 | 2 | 0 | 0 |
ALT | 1 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 1 | 1 | 0 |
Alkaline phosphatase | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 0 |
Creatinine | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 |
AST=aspartate aminotransferase; ALT=alanine aminotransferase.