Table 3. Toxicity.

	Number of patients
	Level 1 (n=3)			Level 2 (n=5)			Level 3 (n=6)			Level 4 (n=7)
Grade	1,2	3	4	1,2	3	4	1,2	3	4	1,2	3	4
Leucocytes	3	0	0	3	0	0	3	0	0	6	0	0
Neutrophiles	1	1	0	1	0	0	2	0	0	3	0	0
Haemoglobin	0	0	0	2	0	0	1	0	0	4	0	0
Platelets	0	0	0	1	0	0	1	0	0	2	0	0
Anorexia	2	0	0	3	0	0	1	3	0	5	0	0
Nausea	0	0	0	2	0	0	1	3	0	6	0	0
Vomiting	1	0	0	0	0	0	2	1	0	3	0	0
Diarrhoea	1	0	0	0	0	0	0	0	0	0	0	0
Mucositis	0	0	0	0	0	0	0	0	0	0	0	0
Fatigue	2	0	0	2	0	0	2	0	0	2	0	0
Gastritis	0	0	0	0	0	0	0	1	0	0	0	0
Duodenal ulcer	0	0	0	0	0	0	0	1	0	0	0	0
Bilirubin	1	0	0	0	0	0	0	0	0	0	0	0
Hypoalbuminaemia	1	0	0	1	0	0	3	0	0	5	0	0
AST	1	0	0	1	0	0	4	0	0	2	0	0
ALT	1	0	0	0	0	0	3	0	0	1	1	0
Alkaline phosphatase	0	0	0	0	0	0	1	0	0	2	0	0
Creatinine	0	0	0	0	0	0	1	0	0	0	0	0

AST=aspartate aminotransferase; ALT=alanine aminotransferase.