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. 2007 Jan 23;96(2):321–328. doi: 10.1038/sj.bjc.6603543

Table 1. Genes differentially expressed in lymph node micrometastases when compared with matched primary cervical cancers.

Gene Gene name ID
Upregulated in LN metastases
 AKT v-akt murine thymoma viral oncogenes homologue 1 Hs00178289_m1
 BCL2 B-cell CLL/lymphoma 2 Hs00153350_m1
 CSFR1 Colony-stimulating factor 1 receptor Hs00234617_m1
 EGFR1 Epidermal growth factor receptor Hs00193306_m1
 FGF1 Fibroblast growth factor 1 (acidic) Hs00265254_m1
 MMP3 Matrix metalloproteinase 3 (stromelysin 1, progelatinase) Hs00233962_m1
 MMP9 Matrix metalloproteinase 9 (gelatinase B, 92 kDa gelatinase) Hs00234579_m1
 TGFB Transforming growth factor, beta 1 Hs00171257_m1
     
Downregulated in LN metastases
 APC Adenomatosis polyposis coli Hs00181051_m1
 ARHA Ras homologue gene family, member A Hs00357608_m1
 BRMS1 Breast cancer metastasissuppressor 1 (Interim) Hs00363036_m1
 CCND1 Cyclin D1 (PRAD1: parathyroid adenomatosis 1) Hs00211039_m1
 CCNE1 Cyclin E1 Hs00233356_m1
 CD44 CD44 antigen (homing function and Indian blood group system) Hs00153310_m1
 ERBB2 v-erb-b2 erythroblastic leukaemia viral oncogenes homologue 2 Hs00170433_m1
 HLA-DPB1 Major histocompatibility complex, class II, DP beta 1 Hs00157955_m1
 ITGAX Integrin, alpha X (antigen CD11C (p150), alpha polypeptide) Hs00174217_m1
 JUN v-jun sarcoma virus 17 oncogene homologue (avian)) Hs00277190_m1
 KLK6 Kallikrein 6 (neurosin, zyme) Hs00160519_m1
 LMNB1 Lamin B1 Hs00194369_m1
 MDM2 Mdm2, transformed 3T3 cell double minute 2, p53-binding protein Hs00242813_m1
 MMP1 Matrix metalloproteinase 1 (interstitial collagenase) Hs00233958_m1
 MMP7 Matrix metalloproteinase 7 (matrilysin, uterine) Hs00159163_m1
 MMP11 Matrix metalloproteinase 11 (stromelysin 3) Hs00171829_m1
 MMP14 Matrix metalloproteinase 14 (membrane-inserted) Hs00237119_m1
 MSH2 mutS homologue 2, colon cancer, nonpolyposis type 1 (Escherichia. coli) Hs00179887_m1
 MUC1 Mucin 1, transmembrane Hs00410317_m1
 MYC v-myc myelocytomatosis viral oncogenes homologue (avian) Hs00153408_m1
 NME1 Nonmetastatic cells 1, protein (NM23A) expressed in Hs00264824_m1
 SERPINB5 Serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member5 Hs00184728_m1
 SRC v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homologue (avian) Hs00178494_m1
 VCAM1 Vascular cell adhesion molecule 1 Hs00174239_m1
 VIM Vimentin Hs00185584_m1
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