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. 2007 Jan 23;96(2):231–240. doi: 10.1038/sj.bjc.6603549

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Copyright © 2007 Cancer Research UK

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Pt-Adduct formation in DNA after exposure of WiDr, H630 and SW1116 cells to OHP with or without TFT in different schedules. The cell lines were exposed 24 h to 200 μM OHP alone or with 10 μM TFT, either simultaneously and/or with a 4 h preincubation period (preTFT). To determine retention of the formed Pt adducts the cells were incubated an additional 3 h in drug-free medium (DFM). Values are Means±s.e.m. (n=4). ^*P<0.05 compared to 24 h OHP. nd=nothing detected.