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. 2007 Jan 16;96(3):457–463. doi: 10.1038/sj.bjc.6603559

Figure 4.

Figure 4

Changes in the hENT1 × dCK/RRM1 × RRM2 expression ratio in gemcitabine-resistant PCI43, PK1, and KLM1 subclones. Value of the ratio in parental cells was set as 1.0. The ratio of hENT1 × dCK/RRM1 × RRM2 expression progressively decreased in the process of acquired gemcitabine resistance. P: parental cells, G: gemcitabine resistant.