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. 2007 Jan 16;96(3):457–463. doi: 10.1038/sj.bjc.6603559

Figure 5.

Figure 5

Significant correlation between the IC50 of gemcitabine and the value of hENT1 × dCK/RRM1 × RRM2 expression ratio in eight pancreatic cancer cell lines (P=0.0029). Cells with a higher hENT1 × dCK/RRM1 × RRM2 expression ratio showed higher gemcitabine chemosensitivity, whereas cells with a lower ratio showed higher chemoresistance.