Table 2. Clinicopathologic characteristics and presence of p53 mutation of LUL-NDE and dysplasia.
| LUL-NDE (n=137) | Dysplasia (n=15) | P-value | |
|---|---|---|---|
| Mean size (mm) | 4 | 9 | 0.032 |
| Range (mm) | 1–6 | 5–20 | |
| Shape of LUL | |||
| Oval | 108 | 5 | <0.0001 |
| Irregular | 29 | 10 | |
| Location | |||
| Upper third | 19 | 1 | 0.441 |
| Middle third | 90 | 9 | |
| Lower third | 28 | 5 | |
| P53 mutation | |||
| Present | 5 | 5 | <0.0001 |
| Absent | 132 | 10 | |
| Hotspot mutation (10 samples with p53 mutation) | |||
| Present | 1 | 2 | 0.490 |
| Absent | 4 | 3 | |
LUL-NDE=Lugol-unstained lesion with non-dysplastic epithelium; location=location of the oesophagus.