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. 2007 Feb 6;96(4):623–630. doi: 10.1038/sj.bjc.6603609

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Copyright © 2007 Cancer Research UK

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Preclinical EBV serologic profiles of NPC. Fifty-six NPC cases detected from the seropositive group were followed up clinically and serologically for various periods from the time of enrollment to times of diagnosis (month 0). Cases were separated into three categories (types I, II and III) according to their preclinical serologic profiles: serum VCA IgA of type III cases fluctuated between ⩾cutoff titre (closed symbols) and < cutoff titre (open symbols) during follow-up; that of type II cases fluctuated initially and rose to ⩾cutoff titre at or before diagnosis; and that of type I cases were sustained at ⩾cutoff titre throughout follow-up and at diagnosis.