Table 2. Summary data for 33 primary MGCTs (22 YSTs & 11 Germinomas), listing those CNIs that show a statistically significant association (P<0.05), with regard to a particular attribute. In the ‘Comparison’ column the numbers in brackets refer to the number of cases in the compared categories.

Comparison	Over-representation of CNI	CNI	P-value	Difference (95%CI)
Histology (germinoma vs YST) (11 vs 22)	YST	1p−	0.003	63.6% [27.0%, 88.1%]
		6q−	0.004	59.1% [21.9%, 82.9%]
		3p+	0.02	45.5% [7.1%, 72.5%]
Gonadal cases (ovarian vs testicular) (17 vs 7)	Testicular tumours	3p+	0.02	53.8% [8.3%, 91.8%]
		8q−	0.04	42.9% [0.2%, 84.8%]
Age (<5 vs ⩾5 years) (14 vs 19)	Age <5 years old	1p−	0.01	−43.6% [−76.2%, −9.1%]
		4q−	0.02	−41.4% [−73.6%, −6.3%]
		4p−	0.03	−37.6% [−71.3%, −2.6%]
		6q−	0.02	−43.2% [−75.8 %, −8.0%]
YST cases only, age (<5 vs ⩾5) (14 vs 8)	Age ⩾5 years old	3q+	0.03	50.0% [6.5%, 87.9%]
12p gain (association with other CNIs)	12p gain present (n=14)	12q+	0.01	46.6% [11.9%, 77.7%]
	12p gain absent (n=19)	16p−	0.04	−36.8% [−67.9%, −3.2%]
12p gain cases only, age (<5 vs ⩾5) (4 vs 10)	Age <5 years old	11q+	0.01	−75.0% [−99.8%, −15.9%]
		6q−	0.02	−70.0% [−98.3%, −9.2%]
		2p+	0.04	−65.0% [−99.4%, −3.8%]
		3p+	0.04	−65.0% [−99.4%, −3.8%]
YST cases only, 12p gain (association with other CNIs)	12p gain present (n=7)	6q−	0.009	60.0% [17.5%, 92.4%]
		12q+	0.01	57.1% [11.0%, 91.7%]
	12p gain absent (n=15)	16p−	0.04	−46.7% [−81.5%, −3.4%]