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. 2007 Feb 13;96(5):725–731. doi: 10.1038/sj.bjc.6603607

Figure 1.

Figure 1

Examples of carboplatin pharmacokinetically guided dosing and exposure (AUC) in individual patients showing (A) a dose reduction implemented on day 3 to achieve a cumulative AUC of 19.6 μg ml−1.min over 5 days of treatment and (B) dose increases on days 3 and 5 resulting in a cumulative AUC of 19.3 μg ml−1.min.