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. 2007 Feb 13;96(5):725–731. doi: 10.1038/sj.bjc.6603607

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Copyright © 2007 Cancer Research UK

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Correlation between actual carboplatin exposure (AUC) and platinum–DNA adduct levels measured in peripheral blood leucocytes obtained 24 h after high-dose carboplatin administration on day 1 of a course of treatment. Data represents samples analysed from six patients receiving carboplatin on day 1 of high-dose carboplatin treatment (MMT 98 study) and three patients receiving carboplatin on day 1 of each of two courses of a high-dose carboplatin window study (MMT 98).