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| Patient | Study day | Carboplatin dose (mg) | Carboplatin AUC (mg ml−1 .min) | Pt-DNA adducts (nmol g−1DNA) |
|---|---|---|---|---|
| 1 | 1 | 522 | 5.2 | 2.28 |
| 5 | 203 | 1.9 | 6.99 | |
| 2 | 1 | 380 | 2.5 | 0.24 |
| 5 | 860 | 7.8 | 2.21 | |
| 3 | 1 | 732 | 5.1 | 0.59 |
| 5 | 534 | 5.8 | 4.06 | |
| 4 | 1 | 418 | 3.8 | 0.57 |
| 5 | 418 | 4.2 | 3.21 |
