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. 2007 Mar 13;96(7):1047–1051. doi: 10.1038/sj.bjc.6603669

Table 2. Molecular biomarkers analysis and correlations with PFS-6.

  N (%) PFS-6 P
EGFR by FISH (n=19)
 Genetic gain 9 (47.3%) 0 NS
 Disomy 10 (52.7%) 30%  
       
EGFR by IHC (n=21)      
 Positive 8 (38.1%) 0 NS
 Negative 13 (61.9%) 23%  
       
p-Akt by IHC (n=21)
 Positive 10 (47.6%) 10% NS
 Negative 11 (52.4%) 18%  

EGFR=Epidermal growth factor receptor; FISH=fluorescence in situ hybridization; IHC=immunohistochemistry; NS, nonsignificant; p-Akt=phosphorylated Akt; PFS-6=progression-free survival at 6 months.