Table 2. Copy number levels at the 17q23 amplicon relative to chromosome 17 centromere in eight primary breast tumours by FISH.
|
Probe setsa
|
|||
|---|---|---|---|
| Tumour number | Ab | Bc | Cd |
| High | |||
| 133 | 1.5 | Ampe | 3 |
| 206 | Ampe | Ampe | 2.5 |
| 209 | Ampe | Ampe | Ampe |
| 236 | 1 | >5 | 1 |
| Moderate | |||
| 249 | 1.5 | 3.5 | 1 |
| 251 | 3 | 3.5 | 3.5 |
| 255 | 2 | 3 | 2 |
| 256 | 3.5 | 3.5 | 3 |
FISH=fluorescence in situ hybridisation.
a
See Materials and Methods.
b
Includes RAD51C-PPM1E genes.
c
Includes PPM1D gene.
d
Includes CYB561-ACE-KCNH6-WDR68 genes.
e
Tight cluster of signals indicative of amplification.