Table 2. List of the 10 more up- and downregulated genes in the comparisons PDTC/normal thyroid and ATC/normal thyroid.
| Gene | LBFC |
|---|---|
| The 10 genes more upregulated in the comparison PDTC/normal thyroid | |
| T-LAK cell-originated protein kinase (PBK) | 66.95 |
| Prostate differentiation factor (GDF15) | 43.56 |
| Anillin, actin-binding protein (scraps homolog, Drosophila) (ANLN) | 39.80 |
| Leucine zipper protein FKSG14 (FKSG14) | 31.82 |
| Hyaluronan-mediated motility receptor (RHAMM) (HMMR) | 28.71 |
| Activin β E (INHBE) | 27.29 |
| Discs, large homolog 7 (Drosophila) (DLG7) | 24.57 |
| Thymidylate synthetase (TYMS) | 24.14 |
| Topoisomerase (DNA) II α 170 kDa (TOP2A) | 23.84 |
| Asp (abnormal spindle)-like, microcephaly associated (Drosophila) (ASPM) | 23.64 |
| The 10 genes more downregulated in the comparison PDTC/normal thyroid | |
| Lumican (LUM) | −233.11 |
| Mucin 7, salivary (MUC7) | −152 |
| Solute carrier family 26, member 4 (SLC26A4) | −133.11 |
| Histatin 3 (HTN3) | −132.01 |
| Histatin 1 (HTN1) | −122.6 |
| Integral membrane protein 2A (ITM2A) | −107.75 |
| Statherin (STATH) | −98.39 |
| Amylase, α 2A; pancreatic (AMY2A) | −93 |
| S100 calcium-binding protein A8 (calgranulin A) (S100A8) | −88.3 |
| Homo sapiens-transcribed sequence with weak similarity to protein ref:NP_060312.1 (H. sapiens) hypothetical protein FLJ20489 [Homo sapiens] | −79.35 |
| The 10 genes more upregulated in the comparison ATC/normal thyroid | |
| Homo sapiens-transcribed sequences | 54.26 |
| Phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1) | 46.41 |
| Fibronectin 1 (FN1) | 41.06 |
| Melanoma antigen, family A, 6 (MAGEA6) | 31.36 |
| L1 cell adhesion molecule (hydrocephalus, stenosis of aqueduct of Sylvius 1, MASA (mental retardation, aphasia, shuffling gait and adducted thumbs) syndrome, spastic paraplegia 1) (L1CAM) | 30.98 |
| Gb:AF043337.1 /DB_XREF=gi:12641914 /GEN=IL8 / FEA=FLmRNA /CNT=1 /TID=Hs.624.1 /TIER=FL /STK=0 /UG=Hs.624 /LL=3576 /DEF=Homo sapiens interleukin 8 C-terminal variant (IL8) mRNA, complete cds. / PROD=interleukin 8 C-terminal variant /FL=gb:AF043337.1 | 30.82 |
| E2F transcription factor 7 (E2F7) | 22.83 |
| Human full-length cDNA 5′-end of clone CS0DK007YB08 of HeLa cells of Homo sapiens (human) | 20.93 |
| Melanoma antigen, family A, 3 (MAGEA3) | 19.99 |
| Anillin, actin-binding protein (scraps homolog, Drosophila) (ANLN) | 19.74 |
| The 10 genes more downregulated in the comparison ATC/normal thyroid | |
| Histatin 3 (HTN3) | −380.67 |
| Solute carrier family 26, member 7 (SLC26A7) | −253.51 |
| Histatin 1 (HTN1) | −198.24 |
| Mucin 7, salivary (MUC7) | −177.54 |
| Glycine amidinotransferase (L-arginine:glycine amidinotransferase) (GATM) | −159.71 |
| Solute carrier family 26, member 4 (SLC26A4) | −149.79 |
| Immunoglobulin J polypeptide, linker protein for immunoglobulin α and μ polypeptides (IGJ) | −127.34 |
| Thyroglobulin (TG) | −118.95 |
| Thyroid peroxidase (TPO) | −116.25 |
| Integral membrane protein 2A (ITM2A) | −115.31 |
PDTC=poorly differentiated thyroid carcinomas.
ATC=anaplastic thyroid carcinomas.
LBFC=lower bound of fold change.